©2018 by The Johnson Lab.

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Contact

Arlen Johnson, Ph.D.

Principal Investigator

(512) 475-6350

arlen@austin.utexas.edu

The Johnson Lab

at the University of Texas at Austin

Ribosome Biogenesis

The ribosome is one of the most complex machines in the cell. We work on how eukaryotic cells assemble, transport, and test ribosomes for function.  We primarily use yeast as a model system because the molecular techniques, genetic reagents and bioinformatics are more robust for yeast than for any other system.  

Featured Articles

Tsr4 is a cytoplasmic chaperone for the ribosomal protein Rps2 in Saccharomyces cerevisiae. Black JJ, Musalgaonkar S, Johnson AW. Mol. Cell. Biol. 2019 June 10. doi: 10.1128/MCB.00094-19.

Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Zhou, Y, Musalgaonkar, S, Johnson, AW and Taylor, DW. Nat. Commun. 2019 Feb 27;10(1):958. doi: 10.1038/s41467-019-08880-0.

Utp14 interaction with the small subunit processome. Black JJ, Wang Z, Goering LM, Johnson AW. RNA. 2018 24:1214-1228. doi: 10.1261/rna.066373.118.

The T-cell leukemia related rpl10-R98S mutant traps the 60S export adapter Nmd3 in the ribosomal P site in yeast. Patchett S, Musalgaonkar S, Malyutin AG, Johnson AW. PLoS Genet. 2017 Jul 17;13(7):e1006894.

Updates

05/2019          Congratulations Lisa Huang for getting into MD Anderson's graduate school!

05/2019          Congratulations Hana Shin for getting into MD Anderson's graduate school!

05/2019          Congratulations Daniel Loftus for joining Amanda Whipple's lab at Harvard University!

05/2019          Congratulations Andrew Bazley for getting into graduate school at New York University!

03/2019          Congratulations Jamie Yelland on passing your PhD Candidacy Qualification Exam!

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